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These changes in protein expression are likely related to the reset of the circadian clock rhythm by intermittent fasting from dawn to sunset and in line with the results of previous murine studies 13,14

The ProTox-II server was used to determine predicted acute oral toxicity of the phytochemical compounds in rodents based upon 2D structure similarities with 38,000 compounds (provided by the software) and their associated LD50 values

Supplementary material The Supplementary Material for this article can be found online at: References 1 RostellatoRPrompJLeclercHMattaliaSFriggensNCBoichardDet al