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A recent meta-analysis suggested that Se supplementation could lower TSH and TPOAb levels, but only in patients with HT not treated with levothyroxine [82], reassessing the role of selenium in the management of patients with chronic thyroid disease [83]

J Biol Chem., 285 (42), e14e15

NPH represents a rare clinical context in which substantial functional improvement can occur following a defined intervention, offering a unique opportunity to study recovery-associated biology in humans

This aligns with the position of major medical organizations, including the American Cancer Society and National Cancer Institute, which do not recognize coffee enemas as having any proven therapeutic value