6 weeks on tirzepatide and no weight loss Compounded Tirzepatide: My Month GLP-1 Journey & Results No weight loss on Zepbound

We've seen interesting data using infusions of tevogrumab (anti-myostatin) +/- garetosmab (anti-activin A) in combo with #semaglutide (data will also be presented at #ADA2025 ) Bimagrumab: an ActRII blocker with a unique mechanism Inhibits myostatin and activins Increases lean muscle mass while decreasing fat mass Phase 2 Data (JAMA Netw Open, 2021) In adults with T2D and obesity: Fat mass: 20.5% Lean mass: 3.6% Body weight: 6.5% Waist: 9 cm HbA1c: 0.76% BELIEVE Study (NCT05616013) A Phase 2b RCT evaluating: Bimagrumab (currently infusion) vs placebo Alone or with #semaglutide In adults with BMI 30 or 27 with complications Results due at #ADA2025 later this month NCT06643728 A Phase 2 RCT evaluating: Bimagrumab (SUBCUTANEOUSLY) vs placebo Alone or with #tirzepatide In adults with BMI 30 or 27 with complications over 70w Expected completion Jan 2027 If BELIEVE confirms bimagrumabs effects, we may soon have the first anti-obesity drug that builds muscle

According to the American Gastroenterological Association (AGA), most people taking a GLP-1 medication can continue it before an endoscopy as long as they arent having symptoms of delayed stomach emptying and follow the usual fasting instructions for the procedure

We address underlying dysfunction by identifying and correcting: Each IV cocktail is tailored to individual needswhether immune support (high-dose vitamin C, zinc, glutathione), detoxification, or athletic recovery

10.3389/fimmu.2019.01374 320 MetaxasA.KempfS