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All SAEs of death, development of signs of critical illness and severe illness requiring hospitalisation, and AEs as described previously will be reported to the Ethics Committees, the Data and Safety Monitoring Board (DSMB) and to the sponsors of the study within 24 hours of awareness of the event, followed by a final report within 10 days
tuberculosis inside the macrophages and also produced increased levels of IL-2, IL-12, and IFN-, essential for the Th1 response and control of intracellular pathogens
These results indicate a shift toward Firmicutes-dominated dysbiosis in ASD models, while hCiPSC treatment promoted a partial restoration toward a healthier microbial configuration enriched in Bacteroidota and Actinomycetota
