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For example, type 2 diabetes increases FA uptake and oxidation in the heart ( FABP3 , which mediates FA transmembrane trafficking, was downregulated, while CPT1 , which mediates mitochondrial transport and -oxidation, was upregulated

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Autophagy can remove damaged mitochondria that would otherwise release reactive oxygen species (ROS) or micronuclei that act as a source of genomic instability

Yuan J, Li X, Yu S (2024) Global, regional, and national incidence trend analysis of malignant skin melanoma between 1990 and 2019, and projections until 2034