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Personalization Potential Microdosing enables fine-tuning that weekly dosing cannot achieve: Gradual titration: Smaller increments for sensitive individuals Flexible scheduling: Adjust doses around life events Rapid adjustment: Quicker response to side effects or inadequate efficacy Combination strategies: Different doses on different days based on activity 4

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A high concentration of selenium in the culture medium may lead to the occurrence of so-called genotoxic effects [32]