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As indicated in Figure 3, these sequences of molecular events are also another potential set of positive feedback loops

Morin hydrate (100 mg/kg) protects against this renohepatic damage through antioxidant and anti-inflammatory mechanisms, restoring organ function, reducing oxidative stress, and preventing histological damage

This upregulation extends to key antioxidant systems, including glutathione (GSH) and thioredoxin (TRX), which help maintain redox balance and support tumor survival [35]

Therefore, further investigation into the role of NRF2 in psoriasis and the exploration of safe and effective NRF2 activators for psoriasis treatment are warranted