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Patients considering GH modulation should consult their healthcare providers and consider FDA-approved options under endocrinologist guidance, such as recombinant human growth hormone for diagnosed GHD or tesamorelin for specific lipodystrophies [fda.gov]

Contraindications include personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia type 2, uncontrolled severe diabetes, severe renal impairment, or concurrent use of other weight-loss medications

Lower doses still have appetite suppressant effects, and some people may find this helps them maintain their lower weight

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