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12 Discussion To date, there are few studies demonstrating utility of topical glutathione in treating hyperpigmentation, oxidative damage, TEWL, and improving skin elasticity

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PPAR activation suppressed the expression of several genes considered essential in the pathogenesis of OA, including IL-1, inducible nitric oxide synthase, MMP-1, and MMP-13, and prevented the IL-1-induced proteoglycan degradation 38,39

Thus, modulation of GSH levels could be proposed as a therapeutic target in HTLV-1-associated diseases