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A physical exam A blood test An imaging scan If these tests show an elevated thyroid-stimulating hormone (TSH) and low levels of thyroid hormones like free T4, total T3, or free T3 it may be an indication that you have hypothyroidism, says Mayumi Endo, MD, an endocrinologist in Seattle

For patients who regain weight, resuming treatment with the same medication or exploring alternatives like tirzepatide injections (which target two appetite-regulating pathways) provides a sustainable long-term approach aligned with your genetic and metabolic profile

Moreover, in a post hoc analysis of the SURPASS-4 randomized clinical trial, tirzepatide decreased albuminuria and total estimated glomerular filtration rate (eGFR) slopes and nearly halved the risk of a pre-specified composite kidney endpoint (eGFR decline 40%, renal death, kidney failure or new-onset macroalbuminuria) in participants with T2DM and high cardiovascular risk when compared with insulin glargine